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1. 毕业设计（论文）的内容、要求、设计方案、规划等

稀有糖虽然在自然界中含量少，但因具有潜在的生物活性和低毒性使其在膳食、保健、医药等 领域发挥着重要作用。

随着生活品质的提高，人们对膳食和健康的要求越来越高，对食品安全性和药物低毒性越来越关注。

为此，广大糖化学和药物化学工作者需要不断深入研究，从原料和合成方法入手，建立廉价高效的稀有糖合成体系，解决稀有糖产业化生产的难题。

2. 参考文献（不低于12篇）

(1) Fanta, G. F.; Abbott, T. P.; Herman, A. I.; Burr, R. C.; Doane, W. M. Hydrolysis of wheat straw hemicellulose with trifluoroacetic acid. Fermentation of xylose with Pachysolen tannophilus. Biotechnology and bioengineering 1984, 26, 1122.(2) Hu, H.; Liu, H.; Shi, Y. The reaction pathway of the isomerization of D-xylose catalyzed by the enzyme D-xylose isomerase: a theoretical study. Proteins 1997, 27, 545.(3) Jokela, J.; Pastinen, O.; Leisola, M. Isomerization of pentose and hexose sugars by an enzyme reactor packed with cross-linked xylose isomerase crystals. Enzyme and Microbial Technology 2002, 31, 67.(4) Lavarack, B. P.; Griffin, G. J.; Rodman, D. The acid hydrolysis of sugarcane bagasse hemicellulose to produce xylose, arabinose, glucose and other products. Biomass Deng, A.; Ren, J.; Liu, C.; Lu, Q.; Zhong, L.; Peng, F.; Sun, R. Catalytic hydrothermal pretreatment of corncob into xylose and furfural via solid acid catalyst. Bioresour. Technol., 2014, 158, 313.(6) Takagaki, A.; Ohara, M.; Nishimura, S.; Ebitani, K. One-pot Formation of Furfural from Xylose via Isomerization and Successive Dehydration Reactions over Heterogeneous Acid and Base Catalysts. Chemistry Letters, 2010, 39, 838.(7) Tomas-Pejo, E.; Oliva, J. M.; Ballesteros, M.; Olsson, L. Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains. Biotechnology and Bioengineering 2008, 100, 1122.(8) Toteva, M. M.; Silvaggi, N. R.; Allen, K. N.; Richard, J. P. Binding Energy and Catalysis by D-Xylose Isomerase: Kinetic, Product, and X-ray Crystallographic Analysis of Enzyme-Catalyzed Isomerization of (R)-Glyceraldehyde. Biochemistry, 50, 10170.(9) Yang, Y.; Hu, C.-W.; Abu-Omar, M. M. Synthesis of Furfural from Xylose, Xylan, and Biomass Using AlCl3 center dot 6H(2)O in Biphasic Media via Xylose Isomerization to Xylulose. ChemSusChem, 2012, 5, 405.(10) Mannei, E.; Ayari, F.; Mhamdi, M.; Almohalla, M.; Ruiz, A. G.; Delahay, G.; Ghorbel, A. Ammoxidation of C-2 hydrocarbons over Mo-zeolite catalysts prepared by solid-state ion exchange: Nature of molybdenum species. Microporous and Mesoporous Materials, 2016, 219, 77.（11）许伟， 蔡萍， 严明，许琳，欧阳平凯，Thermus thermophilus木糖异构酶与木糖醇的分子对接及模型分析，高等学校化学学报， 2007，28,971-973.（12）朱国萍，程阳，宫春红，徐冲，葡萄糖异构酶的生物工程研究进展，生物化学与生物物理进展，2000，27（2），127-131