1. 毕业设计（论文）的内容和要求

1. 掌握相关文献的查阅方法； 2. 掌握电渗析的原理及其应用； 3. 了解离子交换膜的性能特点以及影响其性能的因素； 4. 掌握四种单核苷酸的物理化学性质及其不同pH值下的解离程度； 5. 了解电渗析法脱色的基本原理，并掌握电渗析法对核苷酸酶解液进行脱色的基本实验操作； 6. 论文内容及形式的要求、字数要求按照学校以及院系相关规定执行。

2. 参考文献

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Journal Of Membrane Science, 2007, 288(1-2): 1-12. [6] Jiang C, Wang Y and Xu T. An excellent method to produce morpholine by bipolar membrane electrodialysis[J]. Separation And Purification Technology, 2013, 115(100-106. [7] Kang M-S, Cho S-H, Kim S-H, et al. Electrodialytic separation characteristics of large molecular organic acid in highly water-swollen cation-exchange membranes[J]. Journal Of Membrane Science, 2003, 222(1-2): 149-161. [8] Kumar M, Tripathi BP and Shahi VK. Electro-membrane process for the separation of amino acids by iso-electric focusing[J]. Journal of Chemical Technology Biotechnology, 2010, 85(5): 648-657. [9] Lee K. A media design program for lactic acid production coupled with extraction by electrodialysis[J]. Bioresour Technol, 2005, 96(13): 1505-1510. [10] Leea EG, Moonb S-H, Changa* YK, et al. Lactic acid recovery using two-stage electrodialysis and its modelling[J]. 1998, 1998, 145(53-66. [11] Madzingaidzo L* and Braun R. Process development and optimisation of lacticacid purification using electrodialysis[J]. Journal Of Biotechnology, 2002, 96(223#8211;239. [12] Shen J-n, Yu J, Huang J, et al. Preparation of highly pure tetrapropyl ammonium hydroxide using continuous bipolar membrane electrodialysis[J]. Chemical Engineering Journal, 2013, 220(311-319. [13] Sun X, Wang Q, Zhao W, et al. Extraction and purification of lactic acid from fermentation broth by esterification and hydrolysis method[J]. Separation And Purification Technology, 2006, 49(1): 43-48. [14] Thang VH, Koschuh W, Kulbe KD, et al. Detailed investigation of an electrodialytic process during the separation of lactic acid from a complex mixture[J]. Journal Of Membrane Science, 2005, 249(1-2): 173-182. [15] Tran ATK, Mondal P, Lin J, et al. Simultaneous regeneration of inorganic acid and base from a metal washing step wastewater by bipolar membrane electrodialysis after pretreatment by crystallization in a fluidized pellet reactor[J]. 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3. 毕业设计（论文）进程安排

1 查阅资料、调研 2015年12月-2015年1月 2 开题报告、制订设计方案 2016年1月 3 实验（设计） 2016年2-4月 4 实验数据分析、总结等 2016年5月15日 5 写出初稿 2016年5月25日 6 修改，写出第二稿 2016年5月30日 7 写出正式稿 2016年6月5日 8 答辩 2016年6月