1. 毕业设计（论文）的内容和要求

毕业论文包含四部分内容：1.文献综述：综述目前关于神经元染色的研究现状；2.合成一类7-甲氧基香豆素为荧光母体的探针分子，学会分析图谱及结构鉴定；3.将合成纯化的染料分子用于神经元成像研究；4.总结；5.参考文献

2. 参考文献

1.Two-photon fluorescence sensors for imaging NMDA receptors and monitoring release of Zn2 from the presynaptic terminal. Biosensors and Bioelectronics 91 (2017) 770#8211;7. 2.Agrawalla, B.K., Chandran, Y., Phue, W.H., Lee, S.C., Jeong, Y.M., Wan, S.Y.D., Kang, N.Y., Chang, Y.T., 2015. J. Am. Chem. Soc. 137, 5355#8211;5362. 3.Aizenman, E., Stout, A.K., Harnett, K.A., Dineley, K.E., McLaughlin, B., Reynolds, I.J., 2000. J. Neurochem. 75, 1878#8211;1888. Baek, N.Y., Heo, C.H., Lim, C.S., Masanta, G., Cho, B.R., Kim, H.M., 2012. Chem. Commun. 48, 4546#8211;4548. 4.Borza, I., Domany, G., 2006. Curr. Top. Med. Chem. 6, 687#8211;695. Bush, A.I., Pettingell, W.H., Multhaup, G., Paradis, M., Vonsattel, J.-P., Gusella, J.F., Beyreuther, K., Masters, C.L., Tanzi, R.E., 1994. Science 265, 1464#8211;1467. 5.Chenard, B.L., Shalaby, I.A., Koe, B.K., Ronau, R.T., Butler, T.W., Prochniak, M.A., Schmidt, A.W., Fox, C.B., 1991. J. Med. Chem. 34, 3085#8211;3090. 6.Chyan, W., Zhang, D.Y., Lippard, S.J., Radford, R.J.J., 2014. Proc. Natl. Acad. Sci. USA 111, 143#8211;148. 7.Dai, Z.R., Ge, G.B., Feng, L., Ning, J., Hu, L.H., Jin, Q., Wang, D.D., Lv, X., Dou, T.-Y., Cui, J.N., Yang, L., 2015. J. Am. Chem. Soc. 137, 14488#8211;14495. 8.Fahrni, C.J., O#8217;Halloran, T.V., 1999. J. Am. Chem. Soc. 121, 11448#8211;11458. Fraker, P.J., King, L.E., 2004. Annu. ReV. Nutr. 24, 277#8211;298. 9.Frederickson, C.J., Koh, J.-Y., Bush, A.I., 2005. 6, pp. 449#8211;462. 10.Gao, Y., Feng, G., Jiang, T., Goh, C., Ng, L., Liu, B., Yang, L., Hua, J., Tian, H., 2015. Adv. Funct. Mater. 25, 2857.

3. 毕业设计（论文）进程安排

2018.02.26-2018.03.26 文献综述 2018.02.26-2018.04.26 探针分子合成 2018.04.26-2018.05.15 细胞核成像实验 2018.05.15-2018.05.30 撰写毕业论文